Yes since Handsontable v0.24.2 and PRO v1.3.3 we added support for node environment. It means that you can install our package via npm and you can include library into your script in commonJS module style.
To install regular Handsontable version run
npm install handsontable and for PRO it is
npm install git+ssh://email@example.com:handsontable/handsontable-pro.git.
Also you can bundle your app with browserify. To bundle Handsontable with all dependencies you should name its dependencies like
browserify app.js -o compiled/main.js -r moment -r pikaday -r zeroclipboard or you can omit bundle dependencies like
browserify app.js -o compiled/main.js and include them into HTML as a script tag.